How City of Hope Eases Documentation Burden
When City of Hope physicians, intake nurses and other users use HopeLLM to create a medical history summary, they can see in a matter of minutes a synopsis and timeline of key events, treatments and other important information, Eftekhari says.
“We also have topical summaries if they want to dig deeper into areas such as radiology, pathology, even psychology and socioeconomic factors — anything where they need to know more,” she says.
HopeLLM’s ease of use (for instance, letting physicians ask questions about medical records in natural language) makes it equally beneficial for patients at the point of care, Nazarian says.
“Instead of the doctor typing or going through papers, they can actually look their patients in the eye and have a conversation, using HopeLLM like an assistant,” Eftekhari says. “We built this to help the clinicians, but when it went live, the patients also loved it, which is fantastic.”
While the team developed the first iteration of HopeLLM relatively quickly, Eftekhari says that was possible only because City of Hope had been on its AI journey for about a decade.
“We had a really good foundation that we’ve been working on for years, so we were able to take these foundational models and use them as parts of the puzzle to bring the first minimum viable product to life,” she says.
HopeLLM uses agentic AI for advanced capabilities such as writing SQL queries automatically and comparing cancer treatments to National Comprehensive Cancer Network guidelines. Working in the cloud provided not only the necessary computing power but also elasticity and access to AI models.
“HopeLLM is the epitome of fantastic agentic AI orchestration,” Nazarian says. “It’s one of the things that people are striving to do, and we’ve done it here.”
READ MORE: Healthcare IT leaders get real on the state of AI in 2026.
Providence Finds Clarity With Patient Messaging
For many providers, responding to patient emails is an ever-increasing workload, from answering routine inquiries to providing medical advice about symptoms. Renton, Wash.-based Providence reached a turning point in late 2022, when emails in Epic MyChart surpassed phone calls as the primary means of communication from patients.
“The in-basket has almost become a new site of care,” says Dr. Ford Parsons, chief medical information officer for AI and engineering.
With 51 hospitals and more than 1,000 clinics, Providence’s increase in messages slowed turnaround time, and caregivers struggled to prioritize urgent requests because they handled messages as they arrived, Parsons says.
“That made us identify an operational — almost clinical — need to come up with a new and better way to help our caregivers respond to patient messages,” he says.
With existing workloads in Microsoft Azure, Parsons says, it made sense to build an advanced natural language processing engine in Azure using OpenAI’s GPT architecture to categorize messages by content and urgency and delegate them to the appropriate group. The cloud’s secure, reliable infrastructure and developer-friendly tools made Azure a good fit and let the team iterate rapidly, he adds.
