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May 04 2026
Artificial Intelligence

AI-Powered Healthcare Wearables: The Next Generation of Remote Patient Monitoring

Advances in artificial intelligence mean today’s wearables can generate meaningful insights, not just create streams of data points. That has opened new possibilities for remote monitoring — and shows promise for preventive care.

The landscape for wearable technology in healthcare has seen a significant shift in the past few years. Much of it stems from recent advances in artificial intelligence, especially the combination of AI and edge computing.

“Historically, there was a lot of physiologic data that was never integrated into care,” says Arjun Mahajan, M.D. candidate at Harvard Medical School. “Now, AI can filter the noise, identify clinically meaningful patterns and trends, and create more discrete and actionable insights.”

AI’s ability to analyze wearable data in real time brings innovation to remote patient monitoring (RPM) and “creates a more continuous model of care,” Mahajan says. It also holds potential for identifying early signals of brain health, enabling proactive autoimmune intervention and learning more about sleep’s impact on health.

READ MORE: How does the smart care continuum improve clinical outcomes?

Transforming Raw Data Into Clinical Insights

Mahajan co-authored a 2025 npj Digital Medicine paper on AI’s role in patient safety and clinical decision-making with Dylan Powell, a physiotherapist and assistant professor at Scotland’s University of Stirling. The paper notes the potential for more personalized care “by continuously adapting interventions and therapeutic guidance based on multidimensional and thus more holistic real-time analysis of patient data.”

If an individual in-person visit is like a movie trailer, Powell says, “wearables offer the bigger picture by capturing all activity.”

AI enhances the value of wearables thanks to its speed and efficiency, he adds. Physiotherapists, who study gait and other physical functions, used to need a lot of time to analyze data and develop predictive algorithms. Not only can AI do this more quickly, but also models can integrate multimodal data from the traditional silos of clinical, academic and consumer wearables.

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Real-Time Data Delivery in Remote Patient Monitoring

David Ebert, chief AI and data science officer at the University of Arizona, also uses the term “big-picture view” to describe what AI and wearables can do for RPM. The true power, he says, comes from the processing capabilities embedded in today’s wearables and implantable devices.

Several years ago, a patient with a pacemaker needed a purpose-built home monitor. Now, pacemakers have Bluetooth sensors that connect to smartphones, aggregate data and send notifications to a patient’s care team.

“We’re taking advantage of the capabilities that people are carrying around on a chip,” Ebert says. “We can do machine learning and predictive analytics on the device.”

There are two keys to making this work. One is continued focus on the efficiency of AI models. Data compression will save bandwidth, and the ability to “pull out the signals” will make a device’s output more valuable to clinicians who don’t have time to look at raw data.

“We don’t want AI models to drain the battery or take up a lot of processing time,” Ebert says. “We don’t want to have bandwidth challenges that exacerbate the digital divide.”

The other important step is integrating streams of data and insights from devices into electronic health record and clinical alerting systems. Otherwise, he notes, clinics will need additional equipment and the resources necessary to set it up.

DISCOVER: Here are the wearable technology trends shaping healthcare.

How to Implement and Scale RPM With AI and Wearables    

Mahajan says that ease of integration is important. “The solutions that tend to be effective and adopted as seamlessly as possible don’t create unnecessary work for clinicians.”

Getting this right may require upgraded data ingestion pipelines that can accommodate high-frequency data streams, Mahajan notes, along with tools that normalize data as it’s aggregated. “Organizations have to shift from systems built for episodes to systems built for continuous data,” he says.

Ebert says another consideration is using devices that have evolved from application programming interfaces to agentic AI interfaces. That way, devices can be deployed, monitored and updated using software instead of specialized hardware, which comes with an upfront cost and need for specialized skills that pose a barrier to adoption. “That’s a game changer for rural hospitals,” he says.

Another common obstacle, says Mahajan, is the single-use predictive model or clinical decision support tool: “Health systems aren’t willing to take on 100 different tools. They’re looking for platforms or systems.”

Of course, there’s also the concern that AI models will replace clinicians. That’s not an issue for Dr. Sairam Parthasarathy, director of the Center for Sleep and Circadian Sciences at the University of Arizona.

Licensed providers are few and far between, he says, and “there are so many people who need our help. People shouldn’t have to get sick before we give them health advice,” and data from wearables and insights from AI models can ensure that won’t happen.

David Ebert
“It’s not just finding out what’s wrong. It’s finding out how to treat patients and give them the quality of life they want without having to move to another location to get that treatment.”

David Ebert Chief AI and Data Science Officer, University of Arizona

The Next Wave of AI and Healthcare Wearables

Parthasarathy says healthcare is at an “inflection point” when it comes to leveraging data from wearables. He’s been studying sleep, which can be a signal of cardiac and neurological issues, as well as circadian rhythm, which impacts hormones, the immune system and organ function. Much of this work is taking place in rural areas, where sleep therapy specialists are scarce. But digital cognitive behavioral therapy for insomnia, augmented by wearable data, can fill care gaps.

Powell is interested in determining whether measurable factors such as air quality and noise pollution adversely impact brain health, which presents a “significant disease burden” as patients age. Meanwhile, Mahajan’s interest is using wearables to monitor flare-ups and other subtle changes in patients with autoimmune conditions and to recommend potential proactive interventions.

For Ebert, proactive treatment enabled by AI, wearables, ambient sensors and remote monitoring has “incredible” potential. He sees a future where continuous data streams from patients and their environment are processed daily, and summaries are sent to care teams that are empowered to reach out, change treatment plans or investigate anomalies.

More important, it’s a future that isn’t limited to patients living in the shadows of the nation’s academic medical centers.

“It’s not just finding out what’s wrong. It’s finding out how to treat patients and give them the quality of life they want without having to move to another location to get that treatment,” Ebert says.

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